Tuesday, Sep 30, 2014
 
search SGN
SERVING SEATTLE AND THE PACIFIC NORTHWEST FOR 40 YEARS!

click to visit advertiser's website


Javascript DHTML Drop Down Menu Powered by dhtml-menu-builder.com

Last Weeks Edition
   
click to visit advertiser's website
click to visit advertiser's website
click to visit advertiser's website
click to visit advertiser's website
click to visit advertiser's website
click to visit advertiser's website




 

 
 

 

 

[Valid RSS]

click to go to advertisers website
to Section One | to Arts & Entertainment
posted Friday, August 29 2014 - Volume 42 Issue 35
NIH finds possible substitute for antiretrovirals
Section One
ALL STORIES
  next story
NIH finds possible substitute for antiretrovirals

by Mike Andrew - SGN Staff Writer

A new NIH (National Institutes of Health) study suggests that HIV-specific antibodies can be effective at blocking HIV from entering human T cells, including HIV derived from so-called 'reservoirs' in HIV-undetectable patients.

The technique, called 'passive immunotherapy,' may prove to be an effective substitute for the antiretroviral medications now used to control HIV, lead researcher Dr. Tae-Wook Chun said.

Chun is a scientist at the National Institute of Allergy and Infectious Diseases, under the umbrella of the NIH.

Finding a way to control HIV without antiretrovirals would be an advantage because of their cost, the potential for cumulative toxicities from lifelong antiretroviral therapy, and the difficulties some patients have adhering to drug regimens and tolerating certain drugs.

In the study, NIH researchers obtained HIV from the latent reservoirs of 29 HIV-positive patients whose antiretroviral therapy completely inhibited viral replication.

One of the ongoing challenges in finding a cure for HIV is dealing with these latent reservoirs of the virus in otherwise healthy HIV-undetectable people. Absent life-long antiretroviral therapy, the latent HIV may begin to replicate itself again, launching a new HIV infection.

But in the laboratory, researchers found that several types of 'neutralizing HIV-specific antibodies,' also called 'bNAbs,' effectively blocked HIV from entering T cells obtained from HIV-negative donors.

In addition, the study demonstrated in the laboratory that these antibodies could completely block HIV replication in T cells obtained from HIV-positive individuals receiving antiretroviral therapy.

Researchers concluded that passive immunotherapy involving bNAbs individually or in combination with other techniques may control HIV even without antiretroviral therapy. Clinical trials are already underway, and more are planned to test the hypothesis, NIH said in a statement.

NIH is a federally funded medical research agency, including 27 Institutes and Centers under the U.S. Department of Health and Human Services. NIH is the primary federal agency conducting basic, clinical, and translational medical research.

Tell a friend:

Share on Facebook  Share on Facebook

Post to MySpace!Share on MySpace!

    Share on Delicious

Share on StumbleUpon!

The woman who found the HIV virus:
Nobel Prize Winner Dr. Françoise Barré-Sinoussi at Fred Hutchinson

------------------------------
Seahawks team up with Free2Luv for anti-bullying campaign
------------------------------
Prominent retired generals say military is ready for Transgender service
------------------------------
There are LGBT allies, and then there was Rita
------------------------------
Excessive Force - Public order and justice require police who reflect and respect those they serve
------------------------------
LGBT Americans report lower well-being than straights
------------------------------
Hacker warns Grindr users about security flaw
------------------------------
Most liberal cities: Seattle tied for #3
------------------------------
Obamacare helps LGBT community, but we still lag behind in healthcare - Report discrimination, WA Insurance Commissioner says
------------------------------
Mariela Castro defied party line and voted against exclusion of HIV-positive and Trans workers
------------------------------
Neo-Nazis attack Gay couple in Athens
------------------------------
13-year-old girl's science project IDs fungus threat to HIV patients
------------------------------
NIH finds possible substitute for antiretrovirals
------------------------------

------------------------------

------------------------------

------------------------------

------------------------------

------------------------------
BREAKING NEWS
------------------------------

------------------------------

------------------------------

------------------------------

------------------------------

------------------------------

------------------------------

------------------------------

------------------------------

------------------------------

------------------------------

------------------------------

------------------------------

------------------------------

------------------------------

------------------------------

------------------------------

------------------------------

------------------------------

------------------------------

------------------------------

------------------------------

------------------------------

------------------------------

------------------------------

------------------------------

------------------------------

click to visit advertiser's website

click to visit advertiser's website
click to visit advertiser's website
click to visit advertiser's website
click to visit advertiser's website
click to visit advertiser's website
click to visit advertiser's website
click to visit advertiser's website
click to visit advertiser's website
click to visit advertiser's website
click to visit advertiser's website
click to visit advertiser's website
click to visit advertiser's website
Seattle Gay Blog post your own information on
the Seattle Gay Blog
 

gay news feeds gay news readers gay rss gay
http://sgn.org/rss.xml | what is RSS? | Add to Google use Google to set up your RSS feed
SGN Calendar For Mobile Phones http://sgn.org/rssCalendarMobile.xml
SGN Calendar http://sgn.org/rssCalendar.xml

Seattle Gay News - SGN
1605 12 Ave., Ste. 31
Seattle, WA 98122

Phone 206-324-4297
Fax 206-322-7188

email: sgn2@sgn.org
website suggestions: web@sgn.org

copyright Seattle Gay News 2014 - DigitalTeamWorks 2014

USA Gay News American News American Gay News USA American Gay News United States American Lesbian News USA American Lesbian News United States USA News
Pacific Northwest News in Seattle News in Washington State News